REDUCED MITOCHONDRIAL PYRUVATE COPYRIGHT EXPRESSION IN HEARTS WITH HEART FAILURE AND REDUCED EJECTION FRACTION PATIENTS: ISCHEMIC VS. NON-ISCHEMIC ORIGIN

Reduced mitochondrial pyruvate copyright expression in hearts with heart failure and reduced ejection fraction patients: ischemic vs. non-ischemic origin

Introduction and objectivesMitochondrial pyruvate copyright (MPC) mediates the entry of pyruvate into mitochondria, determining whether pyruvate is incorporated into the Krebs cycle or metabolized in the cytosol.In heart failure (HF), a large amount of pyruvate is metabolized to lactate in the cytosol rather than being oxidized inside the mitochond

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Effect of Epigallocatechin-3-Gallate on Graft-Versus-Host Disease

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is often complicated by alloreactive donor T-cell-mediated graft-versus-host disease (GvHD).The major polyphenol of green tea, epigallocatechin-3-gallate (EGCG), remtavares.com is an inhibitor of both DNA methyltransferase 1 (DNMT1) and signal transducer and activator of transcription 1

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